BOMBAY “O” BLOOD GROUP
Bombay
Blood Group : It is Called Bombay
Blood Group becauSe Bombay Blood Group was first discovered in Bombay. When
Bombay Blood Group was first encountered, Bombay Blood Group was found not to
be of either group A or B and so was thought to be of Group O. But on further
test, Bombay Blood group did not match even for O-ve or O--ve because of the
absence of Antigen 'h'.
This rare genotype was labelled as the Bombay
Blood Group. If a Bombay Blood Group recipient is not transfused the blood of a
Bombay Blood Group person, it can lead to a haemolytic transfusion reaction,
which can be fatal and lead to death
Bombay phenotype (Bombay Blood group ) is a rare
blood group which shows absence of A,B,H antigens on red cells and presence of anti-A, anti-B and
anti-H antibodies in serum.
The rare individuals with Bombay phenotype do
not express H substance on their red blood Cells and therefore do not bind A or
B antigens. Instead, they produce antibodies to H substance (which is present
on all red cells except those of hh phenotype) as well as to both A and B
antigens and are therefore compatible only with other hh donors .
Individuals with Bombay phenotype blood groups
can only be transfused with blood from other Bombay phenotype individuals.
Given that this condition is very rare to begin with, any person with this
blood group, who needs an urgent blood transfusion, may be simply Out of luck,
as it would be quite unlikely that any blood bank would have any in stock.
If
a Bombay Blood Group recipient is not transfused the blood of a Bombay Blood
Group person, it can lead to a haemolytic transfusion.
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